Too much consume salt, Make autoimmune diseases increasingly plague

Too much salt

Perhaps many who not know what it an autoimmune disease. It is a disease that causes the body's immune system attacks its own healthy cells. Examples such as type 1 diabetes, psoriasis, multiple sclerosis and rheumatoid arthritis.

Yet according to the Department of Health and Human Services Office on Women's Health, U.S., in the U.S. alone there are more than 80 types of autoimmune disease that attacks the 23.5 million Americans.

During this the experts just know, if the autoimmune disease appears due to the body to produce of immune cells or white blood cells named TH17 excessively. However until now the experts can not to determine why some people produce more much TH17 than other people. But there are three separate studies published in the journal Nature that claims to find a number of clues.

Researchers note that cases of autoimmune diseases most occur in Western countries. From it the researchers believe this to occur due to factors a changing environment, especially about lifestyle and eating habits that is related to high consumption of processed foods and fast food.

In other words, this new study agreed says another reason to reduce salt consumption is increased salt intake would lead to autoimmune diseases, including make it last a long time in the body.

The first study using a technology developed by Hongkun Park, a doctor from Harvard University, Cambridge. Park uses a silicone device nanowires to change genes in immune cells without affecting its function. This device also successfully explains how to work TH17 cells.

"These findings are also useful because many experts are still searching for how to control that TH17 cells," said co-worker Park, Aviv Regev, a biologist from the Massachusetts Institute of Technology.

Then on the second study, researchers observed of immune cells resulting in a period of more than 72 hours, especially is serum glucocorticoid kinase 1 (SGK1), which served regulate salt levels in the cell that appears each time a TH17 cell created. With using mice as an object, researchers ensure cells in rats that given a  eating patterns high salt have more much expression of SGK1 well as contained more much TH17 cells than the mice that were in the normal environment.

"If you increase the consumption of salt has gradually from one generation to generation you will have TH17 cells," says one of the researchers Vijay Kuchroo, an immunology expert from Brigham and Women's Hospital in Boston, Massachusetts.

A third study research based on both previous studies. Researchers found a bunch of mice which they given with a high salt foods looks produce more much TH17 cells. Which more convincing again some time later the mice it suffering from severe multiple sclerosis that is called autoimmune encephalomyelitis.

"Very clear from experiments on animals this that there are dramatic effects caused by changes in consumption of salt, from low to high," said researcher David Hafler, head of the neurology department of the Yale School of Medicine in New Haven, Connecticut.

The third conclusion of the study are equally ensure that the salt can trigger the emergence of enzyme that creates TH17 cells. However Hafler reminded that salt may be not just the only one trigger of autoimmune diseases because of genetic factors and environmental keep plays a more important role.

It's just that there is a possibility, that changing eating patterns becomes a low-salt would be beneficial for sufferers autoimmune diseases.